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ANN ARBOR, Mich. – Influenza has hit the University of Michigan campus, with more 528 cases diagnosed since early October.

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During the week of Nov. 8 alone, 313 cases were identified, the Detroit Free Press reported. The Centers for Disease Control and Prevention said investigators are going to the campus because of the rapid spike in cases.

Investigators from the CDC will look at the cases to measure the effectiveness of this year’s vaccine and look at the strain of the cases that have been diagnosed, WDIV reported. The CDC will work with the Michigan Department of Health, the Washtenaw County Health Department and the University of Michigan.

The CDC said this year’s flu activity is low, but the number of public health labs reporting positive tests has been going up in the last week. Those cases have largely been among young adults and children. The CDC credits COVID-19 mitigation measures for the historically low flu activity.

The CDC says the annual flu vaccine remains the best prevention against getting influenza.